PP2B-Aα rabbit pAb

Catalytic activity: A phosphoprotein + H (2)O = a protein + phosphate. Cofactor: Binds 1 Fe (3+) ion per subunit. Cofactor: Binds 1 zinc ion per subunit. function: Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1. online information: Calcineurin entry, similarity: Belongs to the PPP phosphatase family. similarity: Belongs to the PPP phosphatase family. PP-2B subfamily. subcellular location: Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle. subunit: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2, MYOZ1, MYOZ2 and MYOZ3.