PP2B-Aα rabbit pAb
Catalytic activity: A phosphoprotein + H (2)O = a protein + phosphate. Cofactor: Binds 1 Fe (3+) ion per subunit. Cofactor: Binds 1 zinc ion per subunit. function: Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1. online information: Calcineurin entry, similarity: Belongs to the PPP phosphatase family. similarity: Belongs to the PPP phosphatase family. PP-2B subfamily. subcellular location: Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle. subunit: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2, MYOZ1, MYOZ2 and MYOZ3.
Product Specifications
Background
Synonyms
Gene ID
5530
UniProt
Q08209
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human PP2B-Aα
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20264-1.pdf
Subcellular Location
Other Product Names
Gene ID (Human)
5530
SwissProt (Human)
Q08209
Available Sizes
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