Amyloid β-Protein (Human, 1-28)

<strong>Amyloid β-Protein (Human, 1-28)</strong> <strong>Catalog number:</strong> MDP0834 <strong>CAS Number: </strong>874904-91-3 <strong>Sequence: </strong>Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 3262.4 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Ostrowitzki S, Lasser RA, Dorflinger E, Scheltens P, Barkhof F, Nikolcheva T, Ashford E, Retout S, Hofmann C, Delmar P, Klein G, Andjelkovic M, Dubois B, Boada M, Blennow K, Santarelli L, Fontoura P; SCarlet RoAD Investigators. A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease Alzheimers Res Ther. 2017 Dec 8;9(1):95. 2: Whelan CD, Mattsson N, Nagle MW, Vijayaraghavan S, Hyde C, Janelidze S, Stomrud E, Lee J, Fitz L, Samad TA, Ramaswamy G, Margolin RA, Malarstig A, Hansson O. Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer's disease Acta Neuropathol Commun. 2019 Nov 6;7(1):169. 3: Nuutinen T, Huuskonen J, Suuronen T, Ojala J, Miettinen R, Salminen A. Amyloid-beta 1-42 induced endocytosis and clusterin/apoJ protein accumulation in cultured human astrocytes Neurochem Int. 2007 Feb;50(3):540-7. 4: Gaskin F, Finley J, Fang Q, Xu S, Fu SM. Human antibodies reactive with beta-amyloid protein in Alzheimer's disease J Exp Med. 1993 Apr 1;177(4):1181-6. 5: Gaggelli E, Janicka-Klos A, Jankowska E, Kozlowski H, Migliorini C, Molteni E, Valensin D, Valensin G, Wieczerzak E. NMR studies of the Zn2+ interactions with rat and human beta-amyloid (1-28) peptides in water-micelle environment J Phys Chem B. 2008 Jan 10;112(1):100-9. 6: Kapurniotu A, Buck A, Weber M, Schmauder A, Hirsch T, Bernhagen J, Tatarek-Nossol M. Conformational restriction via cyclization in beta-amyloid peptide Abeta(1-28) leads to an inhibitor of Abeta(1-28) amyloidogenesis and cytotoxicity Chem Biol. 2003 Feb;10(2):149-59. 7: Lin SY, Chu HL, Wei YS. Secondary conformations and temperature effect on structural transformation of amyloid beta (1-28), (1-40) and (1-42) peptides J Biomol Struct Dyn. 2003 Feb;20(4):595-601. 8: Kowalik-Jankowska T, Ruta M, Wiśniewska K, Lankiewicz L. Coordination abilities of the 1-16 and 1-28 fragments of beta-amyloid peptide towards copper(II) ions: a combined potentiometric and spectroscopic study J Inorg Biochem. 2003 Jul 1;95(4):270-82. 9: De Strooper B, Simons M, Multhaup G, Van Leuven F, Beyreuther K, Dotti CG. Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence EMBO J. 1995 Oct 16;14(20):4932-8. <a href="https://pubmed.ncbi.nlm.nih.gov/15160315">10: Huang J, Yao Y, Lin J, Ye YH, Sun WY, Tang Dagger WX. The solution structure of rat Abeta-(1-28) and its interaction with zinc ion: insights into the scarcity of amyloid deposition in aged rat brain J Biol Inorg Chem. 2004 Jul;9(5):627-35. </a> <br><strong>Products Related to Amyloid β-Protein (Human, 1-28) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>