αvβ6-IN-1
Product Specifications
UNSPSC Description
αvβ6-IN-1 (compound 28) is a potent and orally active αvβ6 integrin inhibitor with a pIC50 value of 8.1. αvβ6-IN-1 has the potential for the research of idiopathic pulmonary fibrosis[1].
Target Antigen
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/αvβ6-in-1.html
Smiles
COC1=C(C)C=C(C(CC(O)=O)CN2CC(C(F)(CCC3=NC4=C(CCCN4)C=C3)F)C2)C=N1
Molecular Weight
474.54
References & Citations
[1]Hryczanek HF, et al. Core Modifications of GSK3335103 toward Orally Bioavailable αvβ6 Inhibitors with Improved Synthetic Tractability. J Med Chem. 2024 Oct 17.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168521/αvβ6-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168521/
Clinical Information
No Development Reported
Curated Selection
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