Oxyresveratrol

Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger (IC50 of 28.9 μM against DPPH free radicals) . Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC50 value of 1.2 μM for mushroom tyrosinase. Oxyresveratrol is effective against HSV-1, HSV-2 and varicella-zoster virus, and has neuroprotective effects[1][2][3][4].

Product Specifications

CAS Number

[29700-22-9]

Product Name Alternative

Trans-Oxyresveratrol

UNSPSC

12352005

Hazard Statement

H319

Target

Autophagy; HSV; Tyrosinase

Type

Natural Products

Related Pathways

Anti-infection; Autophagy; Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Oxyresveratrol.html

Purity

99.73

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2)C(O)=C1

Molecular Formula

C14H12O4

Molecular Weight

244.24

Precautions

H319

References & Citations

[1]Lorenz. et al. Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: Effect on nitrosative and oxidative stress derived from microglial cells. Nitric Oxide 9 (2) 64-76 (2003) .|[2]Kim, Y.M., Yun, J., Lee, C., et al. Oxyresveratrol and hydroxystilbene compounds. Inhbitory effect on tyrosinase and mechanism of action. J Biol Chem277 (18) 16340-16344 (2002) .|[3]Shaida A Andrabi et al. Oxyresveratrol (trans-2,3′,4,5′-tetrahydroxystilbene) is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia. Brain Res, 2004 Aug 13, 1017 (1-2) :98-107.|[4]Vimolmas Lipipun, et al. Topical cream-based oxyresveratrol in the treatment of cutaneous HSV-1 infection in mice. Antiviral Res. 2011 Aug;91 (2) :154-60.