Climbazole
Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450[2].
Product Specifications
CAS Number
38083-17-9
Product Name Alternative
BAY-e 6975
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Climbazole.html
Concentration
10mM
Purity
98.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)(C)C(C(OC1=CC=C(Cl)C=C1)N2C=CN=C2)=O
Molecular Formula
C15H17ClN2O2
Molecular Weight
292.76
Precautions
H302, H315, H319, H335
References & Citations
[1]Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8 (1) :8161.|[2]Y Kobayashi, et al. Climbazole is a new potent inducer of rat hepatic cytochrome P450. J Toxicol Sci. 2001 Aug;26 (3) :141-50.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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