Climbazole

Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450[2].

Product Specifications

CAS Number

[38083-17-9]

Product Name Alternative

BAY-e 6975

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Climbazole.html

Concentration

10mM

Purity

98.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)(C)C(C(OC1=CC=C(Cl)C=C1)N2C=CN=C2)=O

Molecular Formula

C15H17ClN2O2

Molecular Weight

292.76

Precautions

H302, H315, H319, H335

References & Citations

[1]Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8 (1) :8161.|[2]Y Kobayashi, et al. Climbazole is a new potent inducer of rat hepatic cytochrome P450. J Toxicol Sci. 2001 Aug;26 (3) :141-50.