Skullcapflavone I
Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a[1].
Product Specifications
CAS Number
41060-16-6
Product Name Alternative
Panicolin
UNSPSC
12352005
Target
Elastase; MicroRNA
Type
Natural Products
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/skullcapflavone-i.html
Purity
99.30
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=CC=C2O)OC3=C(OC)C(OC)=CC(O)=C13
Molecular Formula
C17H14O6
Molecular Weight
314.29
References & Citations
[1]Yang B, et al. Anti-cancer, Anti-collagenase and Anti-elastase Potentials of Some Natural Derivatives: In vitro and in silico Studies. J Oleo Sci. 2023;72 (5) :557-570.|[2]Cui J, et al. Skullcapflavone I has a potent anti-pancreatic cancer activity by targeting miR-23a. Biofactors. 2020 Sep;46 (5) :821-830.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
22291116 3x 1.0 µg
Gna11 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
Sign In for Pricing
View Details MBS2089165-01 5x 96 Tests
Human Complement Component 9 (C9) ELISA Kit DIY Materials
Sign In for Pricing
View Details MBS2089165-02 5x 96 Tests + MBS2089471 (Support Pack 1,5x 96 Tests)
Human Complement Component 9 (C9) ELISA Kit DIY Materials
Sign In for Pricing
View Details MBS2089165-03 10x 96 Tests
Human Complement Component 9 (C9) ELISA Kit DIY Materials
Sign In for Pricing
View Details