Skullcapflavone I
Product Specifications
UNSPSC Description
Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a[1].
Target Antigen
Elastase; MicroRNA
Type
Natural Products
Related Pathways
Epigenetics;Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/skullcapflavone-i.html
Purity
96.44
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=CC=C2O)OC3=C(OC)C(OC)=CC(O)=C13
Molecular Weight
314.29
References & Citations
[1]Yang B, et al. Anti-cancer, Anti-collagenase and Anti-elastase Potentials of Some Natural Derivatives: In vitro and in silico Studies. J Oleo Sci. 2023;72(5):557-570.|[2]Cui J, et al. Skullcapflavone I has a potent anti-pancreatic cancer activity by targeting miR-23a. Biofactors. 2020 Sep;46(5):821-830.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N1235/Skullcapflavone-I-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N1235/Skullcapflavone-I-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
41060-16-6
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