MHC02181

MHC02181 is a potent inhibitor of Autotaxin (ATX), with IC50 of 9.41 μM[1].

Product Specifications

CAS Number

[460999-85-3]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mhc02181.html

Solubility

10 mM in DMSO

Smiles

O=C(N1C2=C(SC3=C1C=C(C=C3)Cl)C=CC=C2)CSC4=NN=C(O4)C5=CC=CO5

Molecular Formula

C20H12ClN3O3S2

Molecular Weight

441.91

References & Citations

[1]Elli-Anna Stylianaki, et al. Identification of two novel chemical classes of Autotaxin (ATX) inhibitors using Enalos Asclepios KNIME nodes. Bioorg Med Chem Lett. 2024 Mar 5:103:129690.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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