MHC02181
MHC02181 is a potent inhibitor of Autotaxin (ATX), with IC50 of 9.41 μM[1].
Product Specifications
CAS Number
[460999-85-3]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mhc02181.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=C(SC3=C1C=C(C=C3)Cl)C=CC=C2)CSC4=NN=C(O4)C5=CC=CO5
Molecular Formula
C20H12ClN3O3S2
Molecular Weight
441.91
References & Citations
[1]Elli-Anna Stylianaki, et al. Identification of two novel chemical classes of Autotaxin (ATX) inhibitors using Enalos Asclepios KNIME nodes. Bioorg Med Chem Lett. 2024 Mar 5:103:129690.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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