Dovitinib-RIBOTAC (TFA)
Product Specifications
UNSPSC Description
Dovitinib RIBOTAC TFA is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.
Target Antigen
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dovitinib-ribotac-tfa.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C2=NC3=CC(N4CCN(CCNC(NCCOCCOCCOCCOC5=C(O)C=C(/C=C6C(C(C(OCC)=O)=C(NC7=CC=CC=C7)S/6)=O)C=C5)=O)CC4)=CC=C3N2)=C(N)C8=C(C=CC=C8F)N1.OC(C(F)(F)F)=O
Molecular Weight
1120.13
References & Citations
[1]Zhang P, et al. Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment. J Am Chem Soc. 2021 Aug 25;143(33):13044-13055.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139682A/Dovitinib-RIBOTAC-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139682A/Dovitinib-RIBOTAC-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2759351-69-2
Available Sizes
Curated Selection
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