Dovitinib-RIBOTAC (TFA)
Dovitinib RIBOTAC TFA is an RNA-targeting RIBOTAC degrader that can specifically bind to and degrade pre-miR-21. Dovitinib RIBOTAC TFA can inhibit the metastasis of breast cancer and has anti-tumor activity[1].
Product Specifications
CAS Number
[2759351-69-2]
UNSPSC
12352005
Target
DNA/RNA Synthesis; PPAR; Programmed Cell Death 4 (PDCD4) ; PROTACs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dovitinib-ribotac-tfa.html
Purity
98.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C2=NC3=CC(N4CCN(CCNC(NCCOCCOCCOCCOC5=C(O)C=C(/C=C6C(C(C(OCC)=O)=C(NC7=CC=CC=C7)S/6)=O)C=C5)=O)CC4)=CC=C3N2)=C(N)C8=C(C=CC=C8F)N1.OC(C(F)(F)F)=O
Molecular Formula
C53H57F4N9O12S
Molecular Weight
1120.13
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Browse additional items from our catalog
POM121L12 (NM_182595) Human Tagged Lenti ORF Clone
JUN, Phosphorylated (T239) (Activator Protein 1, AP1, AP-1, c-Jun) (FITC)
JUN, Phosphorylated (T239) (Activator Protein 1, AP1, AP-1, c-Jun) (FITC)
CHMP4C Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
MET (HGF Receptor, HGFR, Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, SF Receptor, HGF/SF Receptor, Tyrosine-Protein Kinase Met, Proto-Oncogene c-Met) (PE) discontinued