GLP-1 moiety from Dulaglutide

GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide. GLP-1 moiety from Dulaglutide is a glucagon-like peptide 1 receptor (GLP-1) agonist. Dulaglitude can be used in researches of diabetes and myocardial injury[1][2][3].

Product Specifications

CAS Number

[1197810-60-8]

Product Name Alternative

[Gly8,36, Glu22]-GLP-1 (7-37)

UNSPSC

12352209

Target

GCGR

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/GLP-1_moiety_from_Dulaglitude.html

Purity

99.59

Solubility

DMSO : 1.96 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCl) |H2O : < 0.1 mg/mL

Smiles

O=C(NCC(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CC4=CNC5=CC=CC=C45)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(NCC(NCC(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC6=CNC=N6)N

Molecular Formula

C149H221N37O49

Molecular Weight

3314.62

References & Citations

[1]Anthony Celeste, et al. Anti-pcsk9-glp-1 fusions and methods for use. United States. US 20160369010 A1. 2015-02-20.|[2]Xi L, et al. Dulaglutide accelerates diabetic wound healing by suppressing Nrf2-dependent ferroptosis in diabetic mice. Peptides. 2025 Mar;185:171366.|[3]Wang R, et al. Dulaglutide Alleviates LPS-Induced Injury in Cardiomyocytes. ACS Omega. 2021 Mar 18;6 (12) :8271-8278. doi: 10.1021/acsomega.0c06326. Erratum in: ACS Omega. 2022 May 26;7 (22) :19040.