LU 2443

LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h[1].

Product Specifications

CAS Number

19703-86-7

UNSPSC

12352005

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lu-2443.html

Smiles

S=C1SC(C2=CC=CC=C2)=[N+](C)[N-]1

Molecular Formula

C9H8N2S2

Molecular Weight

208.30

References & Citations

[1]Neidlein R, et al. Biotransformation und Pharmakokinetik von mesoionischem Didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidin-2-thion (LU 2443) . Untersuchungen zur Pharmakokinetik an Ratten [Biotransformation and pharmacokinetics of mesionic didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidine-2-thione (LU 2443) . Studies on the pharmacokinetics in rats]. Arzneimittelforschung. 1982;32 (11) :1447-52.