Sonlicromanol (hydrochloride)

Sonlicromanol (KH176) hydrochloride, a chemical entity derivative of Trolox, is a blood-brain barrier permeable ROS-redox modulator. Sonlicromanol (KH176) hydrochloride is used in the study for mitochondrial disorders[1].

Product Specifications

CAS Number

[2162149-24-6]

Product Name Alternative

KH176 (hydrochloride)

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sonlicromanol-hydrochloride.html

Concentration

10mM

Purity

99.85

Solubility

DMSO : 170 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

CC1=C(C(C)=C2CC[C@@](C(N[C@@H]3CCCNC3)=O)(OC2=C1C)C)O.[H]Cl

Molecular Formula

C19H29ClN2O3

Molecular Weight

368.90

References & Citations

[1]Ria de Haas, et al. Therapeutic effects of the mitochondrial ROS-redox modulator KH176 in a mammalian model of Leigh Disease. Sci Rep. 2017 Sep 15;7 (1) :11733.