Linoleic acid

Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Product Specifications

CAS Number

[60-33-3]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease; Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Linoleic_acid.html

Purity

99.92

Solubility

0.1 M NaOH : 8.33 mg/mL (ultrasonic; warming; adjust pH to 11 with NaOH; heat to 60°C) |DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCC/C=C\C/C=C\CCCCCCCC(O)=O

Molecular Formula

C18H32O2

Molecular Weight

280.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Jay Whelan. Linoleic Acid. Adv Nutr. 2013 May; 4 (3) : 311–312.|[2]Yuan T, et al. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. Int J Clin Exp Pathol. 2015 May 1;8 (5) :5044-52.