Naproxen glucuronide

Naproxen glucuronide ((S) -Naproxen-β-D-glucuronide) is a non-selective COX inhibitor. Naproxen glucuronide, a metabolite of naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain, fever, swelling, and stiffness[1].

Product Specifications

CAS Number

[41945-43-1]

Product Name Alternative

(S) -Naproxen-β-D-glucuronide

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/naproxen-glucuronide.html

Purity

98.71

Solubility

10 mM in DMSO

Smiles

OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC([C@H](C2=CC3=C(C=C2)C=C(C=C3)OC)C)=O)=O

Molecular Formula

C20H22O9

Molecular Weight

406.38

Precautions

H302, H312, H332

References & Citations

[1]Iwaki M, et al. Stereoselective disposition of naproxen glucuronide in the rat. Drug Metab Dispos. 1995 Oct;23 (10) :1099-103.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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