E1R
Product Specifications
Product Name Alternative
MK-0869; MK-869; L-754030
UNSPSC Description
E1R is a positive allosteric modulator of sigma-1 receptors (Sig1R PAM) with cognition-enhancing activity[1].
Target Antigen
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e1r.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CN1C(C[C@@H]([C@@H]1C)C2=CC=CC=C2)=O)N
Molecular Weight
232.283
References & Citations
[1]Zvejniece L, et al. The cognition-enhancing activity of E1R, a novel positive allosteric modulator of sigma-1 receptors. Br J Pharmacol. 2014 Feb;171(3):761-71.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116463/E1R-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116463/E1R-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1301211-78-8
Available Sizes
Curated Selection
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