E3 Ligase Ligand-linker Conjugate 122
E3 Ligase Ligand-linker Conjugate 122 (Compound 2c) is a conjugation of the E3 ligase ligand and the linker, and can be used for synthesis of PROTAC degrader NR-11c.
Product Specifications
CAS Number
3033187-29-7
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-122.html
Smiles
O=C([C@H]1N(C([C@@H](NC(CCCCCNC(CCCN=[N+]=[N-])=O)=O)C(C)(C)C)=O)C[C@H](O)C1)N[C@H](C2=CC=C(C3=C(C)N=CS3)C=C2)C
Molecular Formula
C33H48N8O5S
Molecular Weight
668.85
References & Citations
[1]Cubillos-Rojas M, et al., Synthesis and Biological Activity of a VHL-Based PROTAC Specific for p38α. Cancers (Basel) . 2023 Jan 18;15 (3) :611.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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