1-PalMitoyl-2-arachidoyllecithin
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells.
Product Specifications
CAS Number
[35418-58-7]
Product Name Alternative
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine; PAPC; PC (16:0/20:4)
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H331, H336, H351, H361, H372, H412
Target
Biochemical Assay Reagents; Endogenous Metabolite
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/1-palmitoyl-2-arachidoyllecithin.html
Concentration
12.79 mM * 500 μL in Chloroform
Purity
99.0
Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@H](COC(CCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
Molecular Formula
C44H80NO8P
Molecular Weight
782.08
Precautions
H302, H315, H319, H331, H336, H351, H361, H372, H412
References & Citations
[1]Gugiu, et al. Protein targets of oxidized phospholipids in endothelial cells. J. Lipid Res. 49, 510-520 (2008) .
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
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