T2857W
T2857W is a mutant peptide that has inhibitory effect on KIX-MLL interaction (IC50=5.67 μM) . T2857W can be used for protein-protein interaction (PPI) and for the study of diseases related to KIX-MLL interaction, such as leukemia, cancer, etc[1].
Product Specifications
UNSPSC
12352209
Target
Histone Methyltransferase
Type
Peptides
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/t2857w.html
Smiles
O=C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]4NCCC4
Molecular Formula
C68H101N15O19S
Molecular Weight
1464.68
References & Citations
[1]Sato N, et al. Rational peptide design for inhibition of the KIX–MLL interaction[J]. Scientific Reports, 2023, 13 (1) : 6330.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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