Sekikaic acid

Sekikaic acid is an α-glucosidase (Glucosidase) and α-amylase (Amylases) inhibitor with hypolipidemic, antioxidant and antidiabetic activities. Sekikaic acid significantly reduces LDL, total cholesterol, and total glyceride levels and causes pancreatic beta cell regeneration[1].

Product Specifications

CAS Number

[607-11-4]

UNSPSC

12352005

Target

Amylases; Glycosidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sekikaic-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(C(OC(C2=C(C=C(C=C2CCC)OC)O)=O)=C(C=C1CCC)OC)O)O

Molecular Formula

C22H26O8

Molecular Weight

418.44

References & Citations

[1]Tatipamula VB, et al. Sekikaic acid modulates pancreatic β-cells in streptozotocin-induced type 2 diabetic rats by inhibiting digestive enzymes. Nat Prod Res. 2021 Dec;35 (23) :5420-5424.