PI3K-IN-1
PI3K-IN-1 (XL-147 derivative 1) is a potent inhibitor of PI3K. PI3K-IN-1 (25 μM) blocks PI3K/Akt signaling pathways[1].
Product Specifications
CAS Number
[1349796-36-6]
Product Name Alternative
XL-147 derivative 1
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PI3K-IN-1.html
Purity
99.93
Solubility
DMSO : 27.5 mg/mL (ultrasonic; warming)
Smiles
COC1=CC(NC2=NC3=CC=CC=C3N=C2NS(C4=CC=C(C=C4)NC(C5=CC=C(C(OC)=C5)C)=O)(=O)=O)=CC(OC)=C1
Molecular Formula
C31H29N5O6S
Molecular Weight
599.66
Precautions
H315, H319, H320
References & Citations
[1]Mingyu Hao, et al. Exploring the Role of SRC in Extraocular Muscle Fibrosis of the Graves' Ophthalmopathy. Front Bioeng Biotechnol. 2020 May 8;8:392.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3K
Available Sizes
Curated Selection
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