I-152
I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA) . I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties[1].
Product Specifications
CAS Number
311343-11-0
UNSPSC
12352211
Target
Keap1-Nrf2
Type
Reference compound
Related Pathways
NF-κB
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/i-152.html
Purity
98.78
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(SCCNC([C@H](CS)NC(C)=O)=O)=O
Molecular Formula
C9H16N2O3S2
Molecular Weight
264.36
References & Citations
[1]Crinelli R, et al. Activation of NRF2 and ATF4 Signaling by the Pro-Glutathione Molecule I-152, a Co-Drug of N-Acetyl-Cysteine and Cysteamine. Antioxidants (Basel) . 2021 Jan 26;10 (2) :175.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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