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MRS 2211 (sodium hydrate)

MRS 2211 sodium hydrate is a competitive P2Y13 receptor antagonist (pIC50= 5.97) . MRS 2211 sodium hydrate is highly selective to the P2Y13 receptor, showing more than 20-fold selectivity compared to the P2Y1 and P2Y12 receptors. MRS 2211 sodium hydrate can be used to further investigate the role of the P2Y13 receptor in different physiological and pathological processes, such as its function in blood cells, the nervous system and the immune system[1].

Product Specifications

CAS Number

[1197030-56-0]

UNSPSC

12352005

Target

P2Y Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease; Others

Assay Protocol

https://www.medchemexpress.com/mrs-2211-sodium-hydrate.html

Purity

97.9

Solubility

H2O : 20 mg/mL (ultrasonic)

Smiles

O=CC1=C(COP(O)(O[Na])=O)C(/N=N/C2=CC([N+]([O-])=O)=CC=C2Cl)=NC(C)=C1O.[H]O[H]

Molecular Formula

C14H13ClN4NaO9P

Molecular Weight

470.69

References & Citations

[1]Kim Y C, et al. Synthesis of pyridoxal phosphate derivatives with antagonist activity at the P2Y13 receptor[J]. Biochemical pharmacology, 2005, 70 (2) : 266-274.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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