TYR, Human (P.pastoris, His)

TYR protein, a copper-containing oxidase, initiates melanin production by catalyzing the hydroxylation of tyrosine to DOPA. This essential step is rate-limiting in the synthesis of melanins and polyphenolic compounds. TYR further enables the oxidation of DOPA to DOPA-quinone and potentially mediates the conversion of DHI to indole-5,6 quinone, playing a crucial role in the intricate cascade of reactions involved in melanin biosynthesis. TYR Protein, Human (P.pastoris, His) is the recombinant human-derived TYR protein, expressed by P. pastoris , with N-His, N-6*His labeled tag. The total length of TYR Protein, Human (P.pastoris, His) is 359 a.a., with molecular weight of ~48 kDa.

HFPRACVSSK NLMEKECCPP WSGDRSPCGQ LSGRGSCQNI LLSNAPLGPQ FPFTGVDDRE SWPSVFYNRT CQCSGNFMGF NCGNCKFGFW GPNCTERRLL VRRNIFDLSA PEKDKFFAYL TLAKHTISSD YVIPIGTYGQ MKNGSTPMFN DINIYDLFVW MHYYVSMDAL LGGSEIWRDI DFAHEAPAFL PWHRLFLLRW EQEIQKLTGD ENFTIPYWDW RDAEKCDICT DEYMGGQHPT NPNLLSPASF FSSWQIVCSR LEEYNSHQSL CNGTPEGPLR RNPGNHDKSR TPRLPSSADV EFCLSLTQYE SGSMDKAANF SFRNTLEGFA SPLTGIADAS QSSMHNALHI YMNGTMSQV