SOD1-Derlin-1 inhibitor-2
Product Specifications
UNSPSC Description
SOD1-Derlin-1 inhibitor-2 (compound 56-59) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-2 attenuates the interactions between Derlin-1 and SOD1mut. SOD1-Derlin-1 inhibitor-2 can be used for the research of amyotrophic lateral sclerosis (ALS)[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sod1-derlin-1-inhibitor-2.html
Purity
99.86
Solubility
DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1=C(N)C2=CC=C(C3=CC=CN=C3)N=C2S1)N(C4=CC=CC=C4)CC=C
Molecular Weight
386.47
References & Citations
[1]Tsuburaya N, et al. A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model. Nat Commun. 2018 Jul 10;9(1):2668.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123982/SOD1-Derlin-1-inhibitor-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123982/SOD1-Derlin-1-inhibitor-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2170170-27-9
Available Sizes
Curated Selection
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