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TC OT 39

Product Specifications

UNSPSC Description

TC OT 39 is a synthetic oxytocin analog, as well as a selective agonist of oxytocin receptor (OXTR, EC50=180 nM). TC OT 39 is also an Avprla vasopressin receptor antagonist with an Ki value of 330 nM. TC OT 39 exhibits sedative effects in mouse models[1].

Target Antigen

Oxytocin Receptor; Vasopressin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tc-ot-39.html

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@H](C(N2CCN(C)CCC2)=S)CCC1)NCC3=CC=C(C(N4CC5=C(N(C)N=C5)NC6=CC=CC=C46)=O)C=C3C

Molecular Weight

600.78

References & Citations

[1]Moy SS, et al. Prosocial effects of an oxytocin metabolite, but not synthetic oxytocin receptor agonists, in a mouse model of autism. Neuropharmacology. 2019 Jan;144:301-311.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-108678/TC-OT-39-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-108678/

Clinical Information

No Development Reported

CAS Number

479232-57-0

Available Sizes

Curated Selection

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