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BT-13

Product Specifications

CAS Number

924537-98-4

UNSPSC Description

BT-13 is a potent and selective glial cell line-derived neurotrophic factor (GDNF) receptor RET agonist independently of GFLs, promoting neurite growth from sensory neurons in vitro and attenuates experimental neuropathy in the Rat[1].

Target Antigen

RET

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Neurological Disease

Purity

99.57

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(OC)C(N2CCN(C(C3=CC=C(F)C=C3C(F)(F)F)=O)CC2)=C1)(N(CC)CC)=O

Molecular Weight

517.54

References & Citations

[1]Sidorova YA, et al. A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat. Front Pharmacol. 2017 Jun 21;8:365.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Clinical Information

No Development Reported

Available Sizes

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