NH2-PEG3-C2-NH-Boc

NH2-PEG3-C2-NH-Boc (PROTAC Linker 15) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2].

Product Specifications

CAS Number

[101187-40-0]

Product Name Alternative

PROTAC Linker 15

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-linker-15.html

Purity

99.88

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NCCOCCOCCOCCNC(OC(C)(C)C)=O

Molecular Formula

C13H28N2O5

Molecular Weight

292.37

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.|[2]Li WH, et al. Myeloid Cell-Triggered In Situ Cell Engineering for Robust Vaccine-Based Cancer Treatment. Adv Mater. 2024 Apr;36 (16) :e2308155.