Saluamine

Saluamine is an important N-dealkylated metabolite of Furosemide (HY-B0135) that is produced by microbial transformation and bile metabolism[1][2].

Product Specifications

CAS Number

[3086-91-7]

UNSPSC

12352005

Hazard Statement

H411

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/saluamine.html

Purity

99.75

Smiles

C1=C(C(=CC(=C1C(=O)O)N)Cl)S(=O)(=O)N

Molecular Formula

C7H7ClN2O4S

Molecular Weight

250.66

Precautions

H411

References & Citations

[1]Yakatan GJ, et al. Absorption, distribution, metabolism, and excretion of furosemide in dogs and monkeys I: analytical methodology, metabolism, and urinary excretion. J Pharm Sci. 1976 Oct;65 (10) :1456-60.|[2]Lin Li, et al. Direct Photolysis Determines the Environmental Fate of Furosemide and Its Metabolite Saluamine in Sunlit Surface Waters. Cite this: ACS EST Water 2025, 5, 4, 1832-1842.