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ANGPTL8/Angiopoietin-like 8, Mouse (H40A, Q44A, Q47A, His)

Selected Variant

HY-P700633

Size: 1 Each

ANGPTL8, a blood lipid regulator, controls serum triglyceride levels and orchestrates metabolic transitions during fasting and refeeding. Its role involves directing fatty acid storage in adipose tissue during the fed state. Though its precise mechanism is not fully understood, ANGPTL8 has been suggested to promote ANGPTL3 cleavage, interacting with ANGPTL3 for regulatory functions in lipid metabolism. ANGPTL8/Angiopoietin-like 8 Protein, Mouse (H40A, Q44A, Q47A, His) is the recombinant mouse-derived ANGPTL8/Angiopoietin-like 8 protein, expressed by E. coli , with C-6*His labeled tag and H40A, Q44A, Q47A inactivating mutations[1].

Product Specifications

Product Name Alternative

ANGPTL8/Angiopoietin-like 8 Protein, Mouse (H40A, Q44A, Q47A, His), Mouse, E. coli

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/angptl8-angiopoietin-like-8-protein-mouse-h40a-q44a-q47a-his.html

Smiles

VRPAPVAPLGGPEPAQYEELTLLFAGALALGAALNGVYRATEARLTEAGHSLGLYDRALEFLGTEVRQGQDATQELRTSLSEIQVEEDALHLRAEATARSLGEVARAQQALRDTVRRLQVQLRGAWLGQAHQEFETLKARADKQSHLLWALTGHVQRQQREMAEQQQWLRQIQQRLHTAALPA

Molecular Formula

624219 (Gene_ID) Q8R1L8 (V16-A198, H40A, Q44A, Q47A) (Accession)

Molecular Weight

21.3 kDa

References & Citations

[1]Jorge F. Haller, et al. ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance. J Lipid Res. 2017 Jun; 58 (6) : 1166-1173.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

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