Nrf2-Activator-12G
Nrf2-Activator-12G (compd 12g) is an activator of Nrf2. Nrf2-Activator-12G induces the expression of nrf2-dependentantioxidant enzymes at both mRNA and protein levels in DAergic neuronal cell. Nrf2-Activator-12G can used in study Parkinson’s Disease[1].
Product Specifications
CAS Number
[1554271-18-9]
UNSPSC
12352005
Target
Keap1-Nrf2
Type
Reference compound
Related Pathways
NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nrf2-activator-12g.html
Purity
99.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(/C=C/C1=CC=CC=C1Cl)(C2=CC=CC=C2OC)=O
Molecular Formula
C15H13ClO3S
Molecular Weight
308.78
References & Citations
[1]Woo SY, et al. Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson's disease therapy. J Med Chem. 2014 Feb 27;57 (4) :1473-87.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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