Nrf2-Activator-12G

Nrf2-Activator-12G (compd 12g) is an activator of Nrf2. Nrf2-Activator-12G induces the expression of nrf2-dependentantioxidant enzymes at both mRNA and protein levels in DAergic neuronal cell. Nrf2-Activator-12G can used in study Parkinson’s Disease[1].

Product Specifications

CAS Number

[1554271-18-9]

UNSPSC

12352005

Target

Keap1-Nrf2

Type

Reference compound

Related Pathways

NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nrf2-activator-12g.html

Purity

99.61

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(/C=C/C1=CC=CC=C1Cl)(C2=CC=CC=C2OC)=O

Molecular Formula

C15H13ClO3S

Molecular Weight

308.78

References & Citations

[1]Woo SY, et al. Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson's disease therapy. J Med Chem. 2014 Feb 27;57 (4) :1473-87.