Polyinosinic acid (sodium)
Polyinosinic acid sodium is the sodium form of Polyinosinic acid (HY-148980) . Polyinosinic acid is a single stranded homonucleic acid, which is a Toll-like Receptor 3 (TLR3) ligand. Polyinosinic acid enhances cellular immune response through TLR3 and TRIF. Polyinosinic acid has potential applications in immune regulation[1].
Product Specifications
CAS Number
[33378-44-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/polyinosinic-acid-sodium.html
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=P(O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=C(C(N=CN3)=O)N=C2)O1.[x].[Na].[x]
Molecular Formula
(C10H13N4O8P) x.xNa
Precautions
H302, H315, H319, H335
References & Citations
[1]Marshall-Clarke S, et al. Polyinosinic acid is a ligand for toll-like receptor 3. J Biol Chem. 2007 Aug 24;282 (34) :24759-66.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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