Lonapalene
Lonapalene (RS4317) is a topically effective 5-lipoxygenase (5-LO) inhibitor.
Product Specifications
CAS Number
[91431-42-4]
Product Name Alternative
RS4317
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/RS4317.html
Concentration
10mM
Purity
99.45
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(OC)C(OC(C)=O)=C2C=CC(Cl)=CC2=C1OC(C)=O
Molecular Formula
C16H15ClO6
Molecular Weight
338.74
References & Citations
[1]Black AK, et al. Pharmacologic and clinical effects of lonapalene (RS 43179), a 5-lipoxygenase inhibitor, in psoriasis. J Invest Dermatol. 1990 Jul;95 (1) :50-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-LOX
Available Sizes
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