Lauric acid
Product Specifications
UNSPSC Description
Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively[1].
Target Antigen
Bacterial; Endogenous Metabolite
Type
Natural Products
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Lauric_acid.html
Purity
99.98
Solubility
0.1 M NaOH : 10 mg/mL (ultrasonic;warming;adjust pH to 11 with NaOH;heat to 60°C)|DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCC(O)=O
Molecular Weight
200.322
References & Citations
[1]Nakatsuji T, et al. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol. 2009 Oct;129(10):2480-8.|[2]Tham YY, et al. Lauric acid alleviates insulin resistance by improving mitochondrial biogenesis in THP-1 macrophages. Mol Biol Rep. 2020 Dec;47(12):9595-9607. |[3]Alves NF, et al. Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats. Basic Clin Pharmacol Toxicol. 2017 Apr;120(4):348-353.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-Y0366/Lauric-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-Y0366/Lauric-acid-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
143-07-7
Available Sizes
Curated Selection
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