Lauric acid

Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively[1].

Product Specifications

CAS Number

[143-07-7]

UNSPSC

12352211

Hazard Statement

H318, H401

Target

Bacterial; Endogenous Metabolite

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Lauric_acid.html

Purity

99.93

Solubility

0.1 M NaOH : 10 mg/mL (ultrasonic; warming; adjust pH to 11 with NaOH; heat to 60°C) |DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCC(O)=O

Molecular Formula

C12H24O2

Molecular Weight

200.32

Precautions

H318, H401

References & Citations

[1]Nakatsuji T, et al. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol. 2009 Oct;129 (10) :2480-8.|[2]Tham YY, et al. Lauric acid alleviates insulin resistance by improving mitochondrial biogenesis in THP-1 macrophages. Mol Biol Rep. 2020 Dec;47 (12) :9595-9607. |[3]Alves NF, et al. Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats. Basic Clin Pharmacol Toxicol. 2017 Apr;120 (4) :348-353.