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7-Azaspiro[3.5]nonane-2-ethanol

7-Azaspiro[3.5]nonane-2-ethanol is a PROTAC linker can be used in the synthesis of PROTAC, KTX-951 (HY-148290) [1].

Product Specifications

CAS Number

[1370211-12-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/7-azaspiro-3-5-nonane-2-ethanol.html

Smiles

OCCC1CC2(C1)CCNCC2

Molecular Formula

C10H19NO

Molecular Weight

169.26

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Walker D H, et al. Degraders targeting both IRAK4 and IMiD substrates show combinatorial effects leading to broader activity with durable and complete regressions in MYD88 mutant lymphoma xenografts in vivo. Cancer Research, 2020, 80 (16_Supplement) : 5222-5222.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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