Prostaglandin D2 methyl ester

Prostaglandin D2 methyl ester is a prodrug form of Prostaglandin D2. Prostaglandin D2 methyl ester binds to the human and mouse PGD2 receptors (DP and CRTH2) with Ki values of 160 nM, 175 nM, 460 nM, and 270 nM for mCRTH2, mDP, hCRTH2, and hDP, respectively[1].

Product Specifications

CAS Number

[49852-81-5]

UNSPSC

12352211

Hazard Statement

H225, H319, H336, H360

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/prostaglandin-d2-methyl-ester.html

Concentration

13.64 mM * 200 μL in Methyl acetate

Purity

97.1

Solubility

10 mM in DMSO

Smiles

CCCCC[C@H](O)/C=C/[C@@H]1[C@H]([C@H](CC1=O)O)C/C=C\CCCC(OC)=O

Molecular Formula

C21H34O5

Molecular Weight

366.49

Precautions

H225, H319, H336, H360

References & Citations

[1]Hiroyuki Hirai, et al. Gene structure and functional properties of mouse CRTH2, a prostaglandin D2 receptor. Biochem Biophys Res Commun. 2003 Aug 8;307 (4) :797-802.