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APRIL/TNFSF13 Trimer, Cynomolgus (HEK293, His-Flag-Avi)

Selected Variant

HY-P77564-01

Size: 20 µg

APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process[1]. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture[2]. APRIL protein has been widely used in the study of lymphatic malignancies. APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. APRIL/TNFSF13 Trimer Protein, Cynomolgus (HEK293, His-Flag-Avi) is produced by HEK293 cells (K112-L250) with N-terminal His, Avi, and Flag tags.

Product Specifications

Product Name Alternative

APRIL/TNFSF13 Trimer Protein, Cynomolgus (HEK293, His-Flag-Avi), Cynomolgus, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/april-tnfsf13-protein-cynomolgus-hek293-his-flag-avi.html

Purity

95.00

Molecular Formula

/ (Gene_ID) A0A2K5TJA1 (K112-L250) (Accession)

Molecular Weight

Approximately 55-65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Yu G, et al. APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. Nat Immunol. 2000 Sep;1 (3) :252-6.|[2]Nowacka KH, et al. Role of the APRIL molecule in solid tumors. Cytokine Growth Factor Rev. 2021 Oct;61:38-44.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Price

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