Bellidifolin

Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities[1][2][3]. Bellidifolin also acts as a viral protein R (Vpr) inhibitor[4].

Product Specifications

CAS Number

[2798-25-6]

UNSPSC

12352005

Hazard Statement

H302, H312, H315, H319

Target

HIV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bellidifolin.html

Purity

99.74

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C2=C(OC3=C1C(O)=CC=C3O)C=C(OC)C=C2O

Molecular Formula

C14H10O6

Molecular Weight

274.23

Precautions

H302, H312, H315, H319

References & Citations

[1]Zhao ZY, et al. Protective effects of bellidifolin in hypoxia-induced in pheochromocytoma cells (PC12) and underlying mechanisms. J Toxicol Environ Health A. 2017;80 (22) :1187-1192.|[2]Zheng XY, et al. Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. J Ethnopharmacol. 2014 May 14;153 (3) :854-63.|[3]Basnet P, et al. Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ) -induced diabetic rats from Swertia japonica. Planta Med. 1994 Dec;60 (6) :507-11.|[4]Woo SY, et al. Viral protein R inhibitors from Swertia chirata of Myanmar. J Biosci Bioeng. 2019 May 7.