Hirudin
Hirudin is a thrombin inhibitor with blood anticoagulant property. Hirudin has potent anti-thrombotic, wound repair, anti-fibrosis, anti-tumor and anti-hyperuricemia effects. Hirudin also affects diabetic complications, cerebral hemorrhage, and others[1].
Product Specifications
CAS Number
8001-27-2
UNSPSC
12352209
Hazard Statement
H302+H312+H332
Target
Apoptosis; Thrombin
Type
Peptides
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hirudin.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
[Hirudin]
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
[1]Junren C, et al. Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review. Front Pharmacol. 2021 Apr 16;12:660757.|[2]Xie Y, et al. Hirudin improves renal interstitial fibrosis by reducing renal tubule injury and inflammation in unilateral ureteral obstruction (UUO) mice. Int Immunopharmacol. 2020 Apr;81:106249.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Peptides
Clinical Information
Phase 4
Available Sizes
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