Human Motilin Protein

<strong>Human Motilin Protein</strong>_x000D_ <strong>Catalog number:</strong> B2012955_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 11.8 kDa_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Motilin Protein, Human, Recombinant_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Depoortere I, Thijs T, Thielemans L, Keith JC, Van Assche G, Peeters TL. Effect of recombinant human interleukin-11 on motilin and substance P release in normal and inflamed rabbits Regul Pept. 2001 Mar 2;97(2-3):111-9._x000D_ 2: Broad J, Sanger GJ. The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin Br J Pharmacol. 2013 Apr;168(8):1859-67._x000D_ 3: Broad J, Takahashi N, Tajimi M, Sudo M, Góralczyk A, Parampalli U, Mannur K, Yamamoto T, Sanger GJ. RQ-00201894: A motilin receptor agonist causing long-lasting facilitation of human gastric cholinergically-mediated contractions J Pharmacol Sci. 2016 Feb;130(2):60-5._x000D_ 4: Feighner SD, Tan CP, McKee KK, Palyha OC, Hreniuk DL, Pong SS, Austin CP, Figueroa D, MacNeil D, Cascieri MA, Nargund R, Bakshi R, Abramovitz M, Stocco R, Kargman S, O'Neill G, Van Der Ploeg LH, Evans J, Patchett AA, Smith RG, Howard AD. Receptor for motilin identified in the human gastrointestinal system Science. 1999 Jun 25;284(5423):2184-8._x000D_ 5: Sanger GJ. Motilin receptor neuropharmacology: revised understanding Curr Opin Pharmacol. 2012 Dec;12(6):641-6._x000D_ 6: Sanger GJ, Westaway SM, Barnes AA, Macpherson DT, Muir AI, Jarvie EM, Bolton VN, Cellek S, Näslund E, Hellström PM, Borman RA, Unsworth WP, Matthews KL, Lee K. GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility Neurogastroenterol Motil. 2009 Jun;21(6):657-64, e30-1._x000D_ 7: Dass NB, Hill J, Muir A, Testa T, Wise A, Sanger GJ. The rabbit motilin receptor: molecular characterisation and pharmacology Br J Pharmacol. 2003 Nov;140(5):948-54._x000D_ 8: Mitselos A, Peeters TL, Depoortere I. Desensitization and internalization of the human motilin receptor is independent of the C-terminal tail Peptides. 2008 Jul;29(7):1167-75._x000D_ 9: Depoortere I, Thijs T, van Assche G, Keith JC Jr, Peeters TL. Dose-dependent effects of recombinant human interleukin-11 on contractile properties in rabbit 2,4,6-trinitrobenzene sulfonic acid colitis J Pharmacol Exp Ther. 2000 Sep;294(3):983-90._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/18433751">10: Yamamoto I, Kaiya H, Tsutsui C, Sakai T, Tsukada A, Miyazato M, Tanaka M. Primary structure, tissue distribution, and biological activity of chicken motilin receptor Gen Comp Endocrinol. 2008 May 1;156(3):509-14. </a>_x000D_ _x000D_ <strong>Products Related to Human Motilin Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>