Topoisomerase II inhibitor 20 (TFA)
Topoisomerase II inhibitor 20 TFA is a potent topoisomerase II inhibitor with IC50 of 0.98 µM. Topoisomerase II inhibitor 20 TFA can induce apoptosis and has broad-spectrum anticancer activity[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Topoisomerase
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-ii-inhibitor-20-tfa.html
Purity
96.82
Smiles
O=C(C1=CN(CC)C2=C(C=C(F)C(N3CC(C)NCC3)=C2F)C1=O)N/N=C/C4=CC=CS4.OC(C(F)(F)F)=O
Molecular Formula
C24H24F5N5O4S
Molecular Weight
573.54
References & Citations
[1]Adly ME, et al. Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives. Sci Rep. 2024 Mar 14;14 (1) :6175
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158061A/Topoisomerase-II-inhibitor-20-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158061A/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo II
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