(-) -Amosulalol
(-) -Amosulalol ((-) -YM 09538) is an isomer of Amosulalol (HY-106720), an orally active dual inhibitor of α1/β1-adrenergic receptors. Amosulalol exhibits antihypertensive activity by inhibiting α1-adrenergic receptors. Amosulalol reduces the reflex increase in heart rate and plasma renin activity (PRA) in spontaneously hypertensive rats (SHR) by inhibiting β1-adrenergic receptors.
Product Specifications
CAS Number
[94666-15-6]
Product Name Alternative
(-) -YM 09538
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/minus-amosulalol.html
Smiles
O=S(C1=CC([C@@H](O)CNCCOC2=CC=CC=C2OC)=CC=C1C)(N)=O
Molecular Formula
C18H24N2O5S
Molecular Weight
380.46
References & Citations
[1]Pharmacokinetics and metabolism of an alpha, beta-blocker, amosulalol hydrochloride, in mice: biliary excretion of carbamoyl glucuronide
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
