AZD9056
AZD9056 is a P2X7 purinergic receptor antagonist with anticancer activity. AZD9056 can inhibit the invasion and metastasis of cancer stem cells[1].
Product Specifications
CAS Number
345304-65-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
P2X Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/azd9056.html
Smiles
O=C(C1=CC(CCCNCCCO)=CC=C1Cl)NCC2(C[C@H](C3)C4)C[C@H]4C[C@H]3C2
Molecular Formula
C24H35ClN2O2
Molecular Weight
419.00
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Kang Seok-gu, et al. Pharmaceutical composition for treatment of cancer stem cell. WO2019160312A1. 2019-02-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Citation 01
J Pharmacol Sci. 2020 Sep;144 (1) :43-51.|ACS Appl Mater Interfaces. 2025 Feb 5;17 (5) :7521-7538.|Adv Sci (Weinh) . 2025 Nov 6:e14842.|Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870 (1) :166895.|Front Immunol. 2021 Jan 8;11:602016.
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