11β-Prostaglandin F2α
11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs. PGD2-EA is formed in activated RAW 264.7 cells treated with AEA.
Product Specifications
CAS Number
[714966-38-8]
Product Name Alternative
11-epi PGF2α-EA; 11β-PGF2α-EA; 11β-Prostamide F2α
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/11β-prostaglandin-f2α.html
Concentration
12.58 mM * 200 μL in Ethanol
Purity
95.0
Smiles
OCCN(C(CCC/C=C\C[C@@H]1[C@H]([C@H](C[C@@H]1O)O)/C=C/[C@H](CCCCC)O)=O)[H]
Molecular Formula
C22H39NO5
Molecular Weight
397.55
Precautions
H225, H319
References & Citations
[1]BACHUR NR, et al. FATTY ACID AMIDES OF ETHANOLAMINE IN MAMMALIAN TISSUES. J Biol Chem. 1965 Mar;240:1019-24.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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