Thrombospondin-1 (1016-1023) (human, bovine, mouse)

Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide[1].

Product Specifications

CAS Number

[149234-04-8]

UNSPSC

12352209

Target

Apoptosis; CD47

Type

Peptides

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/thrombospondin-1-1016-1023-human-bovine-mouse.html

Purity

98.75

Solubility

DMSO : ≥ 10 mg/mL|H2O : 14.29 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCSC)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

Molecular Formula

C56H81N13O10S

Molecular Weight

1128.39

References & Citations

[1]Chih-Jian Lih, et al. Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes. Genes Dev. 2006 Aug 1;20 (15) :2082-95. |[2]U Johansson, et al. CD47 ligation induces a rapid caspase-independent apoptosis-like cell death in human monocytes and dendritic cells. Scand J Immunol. 2004 Jan;59 (1) :40-9.