Sphingosine Kinase 2 Active from Mouse

<strong>Sphingosine Kinase 2 Active from Mouse</strong>_x000D_ <strong>Catalog number:</strong> B2016601_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 68 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −80°C_x000D_ <strong>Keywords:</strong> SK2, SPHK2, SPK 2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong> _x000D_ 1: Wang D, Han S, Lv G, Hu Y, Zhuo W, Zeng Z, Tang J, Huang Y, Wang F, Wang J, Zhao Y, Zhao G. Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells Gastroenterology. 2023 Dec;165(6):1488-1504.e20. _x000D_ 2: Weigel C, Maczis MA, Palladino END, Green CD, Maceyka M, Guo C, Wang XY, Dozmorov MG, Milstien S, Spiegel S. Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer Cancer Res. 2023 Feb 15;83(4):553-567. _x000D_ 3: Li L, Wang H, Zhang J, Sha Y, Wu F, Wen S, He L, Sheng L, You Q, Shi M, Liu L, Zhou H. SPHK1 deficiency protects mice from acetaminophen-induced ER stress and mitochondrial permeability transition Cell Death Differ. 2020 Jun;27(6):1924-1937. _x000D_ 4: Ranasinghe ADCU, Holohan M, Borger KM, Donahue DL, Kuc RD, Gerig M, Kim A, Ploplis VA, Castellino FJ, Schwarz MA. Altered Smooth Muscle Cell Histone Acetylome by the SPHK2/S1P Axis Promotes Pulmonary Hypertension Circ Res. 2023 Sep 29;133(8):704-719. _x000D_ 5: Rohrbach T, Maceyka M, Spiegel S. Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology Crit Rev Biochem Mol Biol. 2017 Oct;52(5):543-553. _x000D_ 6: Xie D, Hu G, Chen C, Ahmadinejad F, Wang W, Li PL, Gewirtz DA, Li N. Loss of sphingosine kinase 2 protects against cisplatin-induced kidney injury Am J Physiol Renal Physiol. 2022 Sep 1;323(3):F322-F334. _x000D_ 7: Inoue T, Nakamura Y, Tanaka S, Kohro T, Li LX, Huang L, Yao J, Kawamura S, Inoue R, Nishi H, Fukaya D, Uni R, Hasegawa S, Inagi R, Umene R, Wu CH, Ye H, Bajwa A, Rosin DL, Ishihara K, Nangaku M, Wada Y, Okusa MD. Bone marrow stromal cell antigen-1 (CD157) regulated by sphingosine kinase 2 mediates kidney fibrosis Front Med (Lausanne). 2022 Oct 4;9:993698. _x000D_ 8: Qi H, Cole J 2nd, Grambergs RC, Gillenwater JR, Mondal K, Khanam S, Dutta S, Stiles M, Proia RL, Allegood J, Mandal N. Sphingosine Kinase 2 Phosphorylation of FTY720 is Unnecessary for Prevention of Light-Induced Retinal Damage Sci Rep. 2019 May 23;9(1):7771. _x000D_ 9: Zhang ZS, Liu YY, He SS, Bao DQ, Wang HC, Zhang J, Peng XY, Zang JT, Zhu Y, Wu Y, Li QH, Li T, Liu LM. Pericytes protect rats and mice from sepsis-induced injuries by maintaining vascular reactivity and barrier function: implication of miRNAs and microvesicles Mil Med Res. 2023 Mar 13;10(1):13. _x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/38028248">10: Zhao J, Lee MJ. Sphingosine Kinase 2 Knockout Mice Resist HFD-Induced Obesity Through Increasing Energy Expenditure Int J Endocrinol Metab. 2023 Jul 30;21(3):e136539. </a>_x000D_ <br><strong>Products Related to Sphingosine Kinase 2 Active from Mouse can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>