Methyl linolenate

Methyl linolenate is a polyunsaturated fattly acid (PUFA) . Methyl linolenate has an anti-melanogenesis activity with an IC50 of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids[1][2][3][4].

Product Specifications

CAS Number

[301-00-8]

Product Name Alternative

Linolenic acid methyl ester

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Melatonin Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Methyl-linolenate.html

Purity

99.46

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC/C=C\C/C=C\C/C=C\CCCCCCCC(OC)=O

Molecular Formula

C19H32O2

Molecular Weight

292.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Huh S et al. Melanogenesis inhibitory effect of fatty acid alkyl esters isolated from Oxalis triangularis. Biol Pharm Bull, 2010, 33 (7) :1242-5.|[2]Li X et al. Benchmark Calculations for Bond Dissociation Enthalpies of Unsaturated Methyl Esters and the Bond Dissociation Enthalpies of Methyl Linolenate. J Phys Chem A, 2016, Jun 16, 120 (23) :4025-36|[3]Huh S, et al. Melanogenesis inhibitory effect of fatty acid alkyl esters isolated from Oxalis triangularis. Biol Pharm Bull. 2010;33 (7) :1242-5.|[4]Ko GA, et al. Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway. Nutr Res Pract. 2018 Feb;12 (1) :3-12.