Baicalin
Baicalin, as a flavonoid glycoside, is an allosteric carnitine palmityl transferase 1 (CPT1) activator. Baicalin reduces the expression of NF-κB[1][2][3].
Product Specifications
CAS Number
21967-41-9
Product Name Alternative
Baicalein 7-O-β-D-glucuronide
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; HIV; NF-κB
Type
Natural Products
Related Pathways
Anti-infection; Autophagy; NF-κB
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Baicalin.html
Concentration
10mM
Purity
99.17
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C(O)C(O)=C3C(C=C(C4=CC=CC=C4)OC3=C2)=O
Molecular Formula
C21H18O11
Molecular Weight
446.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Lin M, et al. The protective effect of Baicalin against renal ischemia-reperfusion injury through inhibition of inflammation and apoptosis. BMC Complement Altern Med. 2014 Jan 13;14:19.|[2]Ju XN, et al. Baicalin protects against thrombin induced cell injury in SH-SY5Y cells. Int J Clin Exp Pathol. 2015 Nov 1;8 (11) :14021-7.|[3]Dai J, et al. Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis. Proc Natl Acad Sci U S A. 2018;115 (26) :E5896-E5905.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
NF-κB
Available Sizes
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